• JargonWagon@lemmy.world
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      5 hours ago

      Fascists: That drug causes autism, use this one instead (that just so happens to also profit us)

  • qualia@lemmy.world
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    7 hours ago

    Just to clarify the potentially confusing title. This drug came out three months ago in the US, is a version of PrEP (pre-exposure prophylaxis) that only needs to be taken every six months, and is free with most insurances if you’re in an at-risk demo.

    • qualia@lemmy.world
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      9 hours ago

      Free with many insurances though! It may take a little longer to get a “Prior Authorization,” but as long as you say you’re in an at-risk group for HIV (Google these) it will eventually get approved.

      The rationale is that since treating HIV+/AIDS is so astronomically more expensive than merely paying for this once every 6 months PrEP, that insurance actuaries determine the latter to be way more in the insurance company’s interest.

      This is good since it doesn’t require the insurance companies to be ethical, just cheap. But a win-win is still a win-win, so I say take it where you can get em. {Former pharmacist here, feel free to reach out and ask how to get non-addictive drugs covered} 🪿

  • selkiesidhe@sh.itjust.works
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    1 day ago

    Sounds like a good thing therefore the brainworm in charge of health here in the states will surely get it banned. Or at least made to cost several thousand percent more than it costs to make.

    • IphtashuFitz@lemmy.world
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      1 day ago

      Thank goodness the west coast states have created their own health consortium and a bunch of east coast states have followed suit. I live in one of those east coast states, and just got a covid booster no questions asked. It is also covered 100% by my insurance.

  • Confused_Emus@lemmy.dbzer0.com
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    1 day ago

    Generic versions of a groundbreaking injectable HIV-prevention drug should be available for $40 a year in more than 100 countries from 2027, Unitaid and the Gates Foundation said Wednesday.

    Marketed under the brand name Yeztugo by California-based Gilead Sciences, lenacapavir currently costs around $28,000 a year in the United States.

    FUCK GILEAD

    • CheesyFox@lemmy.sdf.org
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      17 hours ago

      vaccine is a scientific term, meaning a weaker (or, rather, as weak as scientifically possible) version of the same virus / bacteria, so that immune system could learn to fight it without dying in the process.

      This is not a vaccine, as has an active substance, that chemically interacts either with our body, HIV’s shell, or both

      • Caveman@lemmy.world
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        7 hours ago

        There are more ways, weak virus, dead virus, modified virus, payload swap virus and an mRNA blast.

        Would love to see this HIV vac get more development and become permanent and a part of infant vaccine routine until it just fucking dies.

        • CheesyFox@lemmy.sdf.org
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          7 hours ago

          of course there are. I was axcited to hear about Vectors when they were developed. It’s nice to see scientists come up with something new

      • Dremor@lemmy.world
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        8 hours ago

        MRNA vaccine works differently if I remember well. Basically instead of injecting the weaker virus itself, they trick the body to produces non-active parts of that pathogens in order to train the body.

    • stoly@lemmy.world
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      21 hours ago

      There are No vaccines for HIV. This is a drug that if taken continually will prevent the virus from taking hold.

      • Tabula_stercore@lemmy.world
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        16 hours ago

        It is an interesting what makes the distinction.

        The core principle of vaccination is training the immune system with a substance so that a disease can be defeated later on.

        Nothing says that a vaccine needs to be an injection. There are injection vaccines that need multiple doses before the immune system reaches a certain level.

        So why would a pill that trains your immune system not be a vaccine?

        • SaveTheTuaHawk@lemmy.ca
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          10 hours ago

          It’s not a vaccine. It does not trigger an immune response. Science says vaccines cannot be pills, they either need to be intramuscular or inhaled aerosol. This is because they are proteins, which get digested through the stomach and gut.

          • Dremor@lemmy.world
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            8 hours ago

            Some vaccine are oral based (but as a liquid, not as pill). We don’t use them in the West as we have robust viccine that are injection based. But those vaccine requires a way more robust supply chain than many third world countries has, so oral vaccine, while not as effective as injection based vaccine, are used there.
            Problem with oral vaccine is that most pathogens are killed by the digestive system so the only one that could be made as a pill would be those who already are acclimated to such a harsh environment (so gut microbiology).
            There are very few digestive disease that would allow for such vaccine vector to be developed, the only one that could these last few decade would be Ebola. But for such a deadly disease (90% mortality if I remember well), the medical community would prioritize the most effective way, which would be injection.

        • CXORA@aussie.zone
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          16 hours ago

          I guess a pill could be a vaccine, but this drug is neither a vaccine nor a pill, so I have no clue why youre bringing this up.

  • MangioneDontMiss@feddit.nl
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    1 day ago

    40 dollars in low income countries. 28,000 dollars in the united states. The drug is made in the united states.

    WTF.

    • sga@piefed.socialM
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      1 day ago

      speaking as a indian - the reason that this is possible because we kinda ignore medical patents and formulations. (using kinda because i do not know the exact wording in law and the cooldown period).

      It should also tell you about the cost of ingredients and manufacturing vs the costs you pay for “rnd for big companies” (who often build upon work done by universities which often are run by public fundiing)

      • SaveTheTuaHawk@lemmy.ca
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        10 hours ago

        Pharmaceutical companies used to do basic research until the 90s. At this point, they are just banks who buy biotechs spun out from NIH research.

        Now that NIH is gone, the industry will atrophy within a decade. There will be no new drugs.

    • SaveTheTuaHawk@lemmy.ca
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      1 day ago

      Makes you wonder if Trump has a point.

      But thanks to RFK and Trump, there will be no more drugs like this in the future. Gilead did the trials, but 95% of the effort behind this was NIH funded. We can’t even guess how many game changing drugs have been cut in 2025.

      • AA5B@lemmy.world
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        1 day ago

        As always Trump completely misunderstands the situation. Yes there’s a point in how exepnsive drugs are in the us, especially relative to other countries. But whether it’s manufactured in the us has almost nothing to do with it.

        The problem is recovering all the development costs from American patients, and more recently just charging what they think the market will bear. We have to fix the complex maze of healthcare and all the levels of profiteering, we have to fix how development costs can be recovered and most of all we need to fix charging what the market will bear. Has everyone already forgotten the outcry over insulin a few years ago. A ceo who should be in jail decided to start charging ten or twenty times the cost, because he could, because us patients are a captive market. Then got away with saying “some of you can use these coupons….”. There’s definitely a point where exploitive business practices have crossed the line and should be considered criminal acts

        • kbobabob@lemmy.dbzer0.com
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          7 hours ago

          A hell of a lot of that is funded by tax payers. They don’t need to recoup money, they need to give the tax payers what they already paid for.

        • SaveTheTuaHawk@lemmy.ca
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          10 hours ago

          Drug development in trials costs $120-200M. Upon approval, Pharma expects $15B +.

          They have proven they would rather a drug not save lives than offer lower profits.

        • Phoenixz@lemmy.ca
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          1 day ago

          The problem is recovering all the development costs

          Yeeeaaahhh, but no.

          There is also a huge amount of plain greed in there, drug companies aren’t exactly known for being very generous to put it mildly. Cost of healthcare in the US is beyond insanely expensive and that isn’t just because Americans are rich, the vast majority aren’t and for many, getting sick is not only a death sentence, it’s also a death sentence to the family as they’ll be stuck with the medical bills that will bankrupt them.

          The US healthcare system is beyond fucked up with corruption and just plain extortion. Wanna live? Say, that’s a nice first born you have there!

            • boonhet@sopuli.xyz
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              1 day ago

              The issue here is that the bigger insurance companies literally set the prices for services and drugs.

              You wanna keep doing business with United, you charge them what they’re willing to pay, otherwise they’ll just reject claims or put you out of network altogether.

              It’s FUBAR.

    • LaLuzDelSol@lemmy.world
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      1 day ago

      I figured this would come up but you’ve gotta remember that drugs are expensive as hell to develop. And it just received US approval in June so it’s not like they have been sitting on this making money for years.

      • SaveTheTuaHawk@lemmy.ca
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        1 day ago

        The cost of drug development is vastly overstated as an excuse. The reality is $100-200M, but pharma expects $14B++ in returns. Little of that goes back into basic research.

        The front end of costs was spent by the NIH, and after that was ended, Pharma is not taking up the slack. It’s not sustainable and pharma will die in a decade.

        • Dozzi92@lemmy.world
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          1 day ago

          Yeah, a lot of these drug companies have ad budgets larger than the R&D budget, but any overhead is used to jack up the prices. I swear ads are sold at inflated prices for the sake of being able to sell high.

        • Gladaed@feddit.org
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          1 day ago

          Just because development of a single drug costs not that much does not mean you don’t need to pay for failed drugs too. If many drugs die during trials someone gotta pay for that. Profitability is a better indicator for greed.

        • LaLuzDelSol@lemmy.world
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          1 day ago

          I’d like to see some sources on those numbers, I couldn’t find any of that when I searched.

  • bassomitron@lemmy.world
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    2 days ago

    And anti vaxxers will make some bullshit claim, making idiots believe it, and it’ll only halfway eliminate HIV.

    • jumperalex@lemmy.world
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      2 days ago

      Not just them, but the religious fuckers who want everyone to suffer “consequences” for the sin of sex. Same ones that freak out about HPV vaccine.

      I know there is a lot of overlap. But it isn’t total.

    • Blackmist@feddit.uk
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      1 day ago

      You know what, if you have HIV and throw your lot in with them then you’ve only got yourself to blame. If they had their way they’d throw you down a well for having it.

      • SpaceCowboy@lemmy.ca
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        1 day ago

        Problem is “that lot” is running the HHS (including the CDC) so people that want medicine in the US may not have access, even if they can afford it (which is becoming more unlikely than before).

        Americans will find some way to blame the democrats for it tho, so the few people that actually vote will just vote in “that lot” again.

  • Aatube@kbin.melroy.orgM
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    2 days ago

    generic versions of a groundbreaking injectable drug to prevent HIV

    The two organisations have entered into separate agreements with Indian pharmaceutical companies to produce cheaper generic versions of lenacapavir – a twice-yearly injection shown to reduce the risk of HIV transmission by more than 99.9 percent – for [more than 100] low- and middle-income countries.

    Marketed under the brand name Yeztugo by California-based Gilead Sciences, lenacapavir currently costs around $28,000 a year in the United States.

    • chiocciola@lemmy.cafe
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      2 days ago

      No no, keep their funding but make a Pharmaceutical company around it and only release pills with enough potency to treat instead of cure

      • NickwithaC@lemmy.worldM
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        2 days ago

        “Hey Jimmy, you weren’t at work yesterday”

        “oh, my AIDS was acting up but I took some Rubitussin, I’m fine now.”

  • Archangel1313@lemmy.ca
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    2 days ago

    “We can end HIV”:

    …as long as we can convince everyone to take it. So, yeah. Good luck with that.

    • BanMe@lemmy.world
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      1 day ago

      Yeah I hate to say it, but I worked in HIV prevention in the late 2000s, and we really thought prep was going to be the end of HIV, along with rigorous testing and linkage to care.

      Since then, HIV rates have exploded in many areas, silently, because we’ve gone fully regressive on sex ed.

      I have friends that became HIV positive before they even knew about prep.

      WTF happened.

  • altkey (he\him)@lemmy.dbzer0.com
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    2 days ago

    The Gates Foundation also announced Wednesday that it had entered into a similar partnership with Indian pharmaceutical company Hetero.

    That’s for bigots to not being ashamed of taking pills against sexually transmited diseases? See, Hetero is in it’s very name, so it’s fine!

    • AA5B@lemmy.world
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      That’s ok, I’m sure it won’t be allowed to sell in the us. Profits will be intact

      • boonhet@sopuli.xyz
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        1 day ago

        Yes, the US won’t get the Hetero, they’ll only get the sparkly $28000 version, called the Homo.